The Biology of Aging and Longevity

Conductor

The Conductor

Welcome aboard this journey into the ticking clock of your own cells. We will explore why nature designed us to fade and how science seeks to push back the horizon of time.

What you will learn

FOUNDATION

Establishes the core vocabulary and essential context you need before going further.

• Identify core biological markers of aging

Station 01: Defining Biological Aging▶

• Explain evolutionary theories regarding lifespan

Station 02: Evolution and Longevity▶

• Describe the role of genes in aging

Station 03: The Genetic Blueprint▶

CORE CONCEPTS

Unpacks the ideas and principles that the subject is built on.

• Analyze telomere shortening during mitosis

Station 04: Telomeres and Cell Division▶

• Examine energy production decline in cells

Station 05: Mitochondrial Dysfunction▶

• Describe protein folding errors in cells

Station 06: Proteostasis Failure▶

• Define epigenetic changes during aging

Station 07: Epigenetic Clocks▶

MECHANICS

Examines how things actually work — the processes, rules, and systems in action.

• Evaluate the impact of zombie cells

Station 08: Cellular Senescence▶

• Discuss stem cell regenerative capacity

Station 09: Stem Cell Exhaustion▶

• Analyze metabolic pathways like mTOR

Station 10: Nutrient Sensing Pathways▶

APPLICATION

Puts knowledge to use through real-world scenarios and practical problems.

• Assess benefits of reduced calorie intake

Station 11: Caloric Restriction Effects▶

• Explore potential anti-aging drug candidates

Station 12: Pharmacological Interventions▶

• Evaluate lifestyle impacts on aging

Station 13: Lifestyle and Longevity▶

SYNTHESIS

Connects everything together and explores broader implications and open questions.

• Discuss future directions in gerontology

Station 14: The Future of Medicine▶

• Critique ethical implications of life extension

Station 15: Ethics of Longevity▶

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The Biology of Aging and Longevity — Learn Biological Sciences | Learning Whistle